Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14273825 | 1.00 | PTPN1 (0.61) | PTPN1PTPN2CDC25BPTGS1PDE4A | |
| SCHEMBL28775429 | 0.84 | PTPN1 (0.62) | PTPN1PTPN2CDC25BPTGS1PDE4A | |
| SCHEMBL14273829 | 0.84 | PTPN1 (0.62) | PTPN1PTPN2CDC25BPTGS1PDE4A | |
| SCHEMBL4762696 | 0.84 | PTPN1 (0.62) | PTPN1PTPN2CDC25BPTGS1PDE4A | |
| SCHEMBL14273776 | 0.83 | PTPN1 (0.64) | PTPN1PTPN2CDC25BPTGS1PDE4A | |
| SCHEMBL4760983 | 0.83 | PTPN1 (0.64) | PTPN1PTPN2CDC25BPTGS1PDE4A | |
| SCHEMBL4716765 | 0.82 | EGFR (0.39) | PTPN1 | |
| SCHEMBL4761018 | 0.80 | PTPN1 (0.57) | PTPN1PTPN2CDC25BPTGS1PDE4A | |
| SCHEMBL14273826 | 0.80 | PTPN1 (0.59) | PTPN1PTPN2CDC25BPTGS1PDE4A | |
| SCHEMBL28775426 | 0.80 | PTPN1 (0.59) | PTPN1PTPN2CDC25BPTGS1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004159-A1 | AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS | Biovitrum AB (publ) (SE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007104790-A1 | AUTOIMMUNE CONDITIONS AND NADPH OXIDASE DEFECTS | BIOVITRUM AB (PUBL) (SE) | 2007-09-20 | — | — | WO | disclosed |