Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515417 | 1.00 | KCNH2 (0.47) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1385516 | 1.00 | KCNH2 (0.47) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4526255 | 1.00 | KCNH2 (0.47) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4515425 | 1.00 | KCNH2 (0.47) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4512263 | 0.91 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL1382165 | 0.91 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL1383966 | 0.91 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL4759255 | 0.91 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL1382167 | 0.91 | KCNH2 (0.46) | KCNH2 | |
| SCHEMBL4514077 | 0.88 | KCNH2 (0.49) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-B1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2008-06-11 | — | — | EP | disclosed |