Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.63 |
| ▸ | FLT4 | P35916 | 2/20 | 0.63 |
| ▸ | KDR | P35968 | 16/20 | 0.63 |
| ▸ | FLT3 | P36888 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 5/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.57 |
| ▸ | RET | P07949 | 2/20 | 0.56 |
| ▸ | GAK | O14976 | 1/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.56 |
| ▸ | STK10 | O94804 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14081284 | 0.93 | KDR (0.68) | PDGFRBFLT4KDRFLT3EGFR | |
| SCHEMBL5556064 | 0.92 | PDGFRB (0.62) | PDGFRBFLT4KDRFLT3EGFR | |
| Hydrochloric Acid SCHEMBL4758921 | 0.91 | PDGFRB (0.61) | PDGFRBFLT4KDRFLT3EGFR | |
| SCHEMBL14081368 | 0.84 | PDGFRB (0.54) | PDGFRBFLT4KDRFLT3EGFR | |
| SCHEMBL14081354 | 0.84 | PDGFRB (0.54) | PDGFRBFLT4KDRFLT3EGFR | |
| SCHEMBL4760833 | 0.84 | KDR (0.69) | PDGFRBFLT4KDRFLT3EGFR | |
| SCHEMBL23703468 | 0.76 | EGFR (0.77) | PDGFRBFLT4KDREGFRHDAC3 | |
| SCHEMBL25682990 | 0.76 | KDR (0.78) | KDRFLT3EGFRRETGAK | |
| SCHEMBL18158179 | 0.75 | EGFR (0.79) | KDRFLT3EGFRRETGAK | |
| SCHEMBL22300265 | 0.75 | EGFR (0.71) | KDRFLT3EGFRRETGAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7413727-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2008-08-19 | — | — | US | disclosed |
| EP-1442751-B1 | Diagnostic imaging technique | GE HEALTHCARE AS (NO) | 2007-06-20 | — | — | EP | disclosed |
| EP-1442751-A1 | Method of imaging | Amersham Health AS (NO) | 2004-08-04 | — | — | EP | disclosed |
| EP-0977600-B1 | CONTRAST AGENTS TARGETTING RECEPTORS ASSOCIATED WITH ANGIOGENESIS | AMERSHAM HEALTH AS (NO) | 2004-06-30 | — | — | EP | disclosed |
| US-20040009122-A1 | Contrast agents | AMERSHAM HEALTH AS (NO) | 2004-01-15 | — | — | US | disclosed |
| US-6610269-B1 | Disease state imaged using a targeted contrast agent of the formula V-L-R, where V is a vector moiety having affinity for an angiogenesis-related endothelial cell receptor, L is a linker, R is a macromolecular or particulate label | AMERSHAM HEALTH AS (NO) | 2003-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009122-A1 | Contrast agents | FLT1, FLT4, KDR | PDGFRB 181/4885FLT4 2/4885KDR 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.