Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 4/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL2219402 | 1.00 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TP53 | |
| Methacrylic Acid SCHEMBL5463979 | 1.00 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TP53 | |
| Methacrylic Acid SCHEMBL2059780 | 1.00 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TP53 | |
| Methacrylic Acid SCHEMBL18140227 | 1.00 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TP53 | |
| Methacrylic Acid SCHEMBL475891 | 1.00 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TP53 | |
| Methacrylic Acid SCHEMBL18140953 | 1.00 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TP53 | |
| Methacrylic Acid SCHEMBL5462229 | 1.00 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TP53 | |
| Methacrylic Acid SCHEMBL2059838 | 1.00 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TP53 | |
| Methacrylic Acid SCHEMBL4653322 | 1.00 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TP53 | |
| Methacrylic Acid SCHEMBL3067708 | 1.00 | TDP1 (0.53) | TDP1TGFBR1TSHROR51E2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218218-A1 | OPTICALLY CLEAR UV AND THERMAL CURING EPOXY COMPOSITIONS | HENKEL AG & CO KGAA (DE) | 2024-07-04 | — | — | US | claimed |
| US-11732158-B2 | Adhesive compositions | HENKEL AG & CO. KGAA (DE) | 2023-08-22 | — | — | US | claimed |
| WO-2023147115-A1 | (METH)ACRYLATE-BASED TOUGHENED ADHESIVES | HENKEL AG & CO. KGAA (DE) | 2023-08-03 | — | — | WO | claimed |
| US-11667820-B2 | Adhesive composition for polarizing plate, polarizing plate, and optical display device | SAMSUNG SDI CO., LTD. (KR) | 2023-06-06 | — | — | US | claimed |
| WO-2023043757-A1 | OPTICALLY CLEAR UV AND THERMAL CURING EPOXY COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2023-03-23 | — | — | WO | claimed |
| EP-3612609-B1 | ADHESIVE COMPOSITIONS | HENKEL AG & CO KGAA (DE) | 2022-12-28 | — | — | EP | claimed |
| US-20200071577-A1 | ADHESIVE COMPOSITION FOR POLARIZING PLATE, POLARIZING PLATE, AND OPTICAL DISPLAY DEVICE | Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) | 2020-03-05 | — | — | US | claimed |
| US-20200040223-A1 | ADHESIVE COMPOSITIONS | Henkel IP & Holding GmbH (DE) | 2020-02-06 | — | — | US | claimed |
| US-20190136102-A1 | ADHESIVE COMPOSITIONS CONTAINING REACTIVE SILSESQUIOXANES | Henkel IP & Holding GmbH (DE) | 2019-05-09 | — | — | US | claimed |
| EP-2924085-B1 | COMPOSITION FOR ENCAPSULATION OF ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DIODE DISPLAY MANUFACTURED USING THE SAME | SAMSUNG SDI CO LTD (KR) | 2019-05-08 | — | — | EP | claimed |
| EP-2924085-A1 | Composition for encapsulation of organic light emitting diode and organic light emitting diode display manufactured using the same | Samsung SDI Co., Ltd. (KR) | 2015-09-30 | — | — | EP | claimed |
| US-20150225626-A1 | ADHESIVE COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2015-08-13 | — | — | US | claimed |
| US-20140235758-A1 | ADHESIVE COMPOSITIONS | Henkel US IP LLC (US) | 2014-08-21 | — | — | US | claimed |
| US-7935472-B2 | Photo-curable resin composition and a method for forming a pattern using the same | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2011-05-03 | — | — | US | claimed |
| US-20100065210-A1 | FLOWABLE NON-SAGGING ADHESIVE COMPOSITIONS | HENKEL CORPORATION (US) | 2010-03-18 | — | — | US | claimed |
| WO-2008057414-A1 | FLOWABLE, NON-SAGGING ADHESIVE COMPOSITIONS | HENKEL CORPORATION (US) | 2008-05-15 | — | — | WO | claimed |
| US-7115676-B2 | Adhesive compositions for bonding passive substrates | HENKEL CORPORATION (US) | 2006-10-03 | — | — | US | claimed |
| US-20030217808-A1 | Adhesive compositions for bonding passive substrates | Henkel IP & Holding GmbH (DE) | 2003-11-27 | — | — | US | claimed |
| EP-1285037-A2 | ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS | Henkel Loctite Corporation (US) | 2003-02-26 | — | — | EP | claimed |
| WO-2001088050-A2 | ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS | HENKEL LOCTITE CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |