Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3944734 | 0.95 | BRD4 (0.50) | BRD4SERPINE1CA1CA2PTPN5 | |
| SCHEMBL3944739 | 0.87 | BRD4 (0.49) | BRD4SERPINE1CA1CA2PTPN5 | |
| SCHEMBL3951354 | 0.87 | BRD4 (0.49) | BRD4SERPINE1CA1CA2PTPN5 | |
| SCHEMBL3952994 | 0.87 | BRD4 (0.49) | BRD4SERPINE1CA1CA2PTPN5 | |
| SCHEMBL4761303 | 0.87 | SERPINE1 (0.46) | BRD4SERPINE1PDE3ACA1CA2 | |
| SCHEMBL4762480 | 0.86 | BRD4 (0.51) | BRD4SERPINE1PDE3ACA1CA2 | |
| SCHEMBL5149516 | 0.86 | CA1 (0.49) | BRD4SERPINE1PDE3ACA1CA2 | |
| SCHEMBL3945870 | 0.86 | BRD4 (0.49) | BRD4SERPINE1PTPN5HSP90AA1HSP90AB1 | |
| SCHEMBL4762525 | 0.84 | CA1 (0.36) | CA1CA2CA12CA4CA6 | |
| SCHEMBL4762731 | 0.83 | BRD4 (0.46) | BRD4SERPINE1PDE3ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001843-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | claimed |
| WO-2007107384-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | claimed |
| EP-2001843-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007107384-A2 | SOLUBLE ADENYLATE CYCLASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | WO | disclosed |