Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4762296 | 0.90 | KDM4E (0.65) | KDM4ETDP1KMT2AATMHTT | |
| SCHEMBL15281340 | 0.89 | KDM4E (0.85) | KDM4ETDP1KMT2AATMHTT | |
| SCHEMBL16690390 | 0.89 | KDM4E (0.82) | KDM4ETDP1KMT2AATMHTT | |
| SCHEMBL15281310 | 0.88 | KDM4E (0.81) | KDM4ETDP1KMT2AATMHTT | |
| SCHEMBL15281339 | 0.87 | KDM4E (1.00) | KDM4ETDP1KMT2AATMHTT | |
| SCHEMBL4718945 | 0.86 | PIK3CG (0.71) | KDM4ETDP1KMT2AATMHTT | |
| SCHEMBL11026144 | 0.85 | DRD3 (0.65) | KDM4ETDP1KMT2AATMHTT | |
| SCHEMBL6302320 | 0.85 | KMT2A (0.62) | KDM4ETDP1KMT2AATMHTT | |
| SCHEMBL16690444 | 0.84 | KDM4E (0.75) | KDM4ETDP1KMT2AATMHTT | |
| SCHEMBL15281332 | 0.84 | KDM4E (0.74) | KDM4ETDP1KMT2AATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230235-B1 | COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES | NEW PHARMA RES SWEDEN AB (SE) | 2008-06-11 | — | — | EP | claimed |
| EP-1230235-B1 | COMPOUNDS WITH ANTIBACTERIAL AND ANTIPARASITIC PROPERTIES | NEW PHARMA RES SWEDEN AB (SE) | 2008-06-11 | — | — | EP | disclosed |
| US-6967205-B1 | Compounds with antibacterial and antiparasitic properties | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-11-22 | — | — | US | disclosed |