Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.35 |
| ▸ | CNR2 | P34972 | 14/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4712909 | 0.90 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL13867149 | 0.87 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL4709376 | 0.86 | CNR1 (0.40) | CNR1CNR2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4710895 | 0.79 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL4711291 | 0.79 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL4712276 | 0.78 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL4713030 | 0.78 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL3153456 | 0.78 | CNR1 (0.54) | CNR1CNR2 | |
| SCHEMBL4711784 | 0.77 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL1029851 | 0.77 | CNR1 (0.45) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863479-B1 | TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS CROSS REFERENCE TO RELATED APPLICATIONS | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-10 | — | — | EP | claimed |