Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 2/20 | 0.30 |
| ▸ | LITAF | Q99732 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1383798 | 1.00 | KCNH2 (0.35) | KCNH2CYP3A4TNFLITAF | |
| SCHEMBL4515843 | 1.00 | KCNH2 (0.35) | KCNH2CYP3A4TNFLITAF | |
| SCHEMBL4516904 | 0.94 | KCNH2 (0.35) | KCNH2CYP3A4 | |
| SCHEMBL4717107 | 0.94 | KCNH2 (0.35) | KCNH2CYP3A4 | |
| SCHEMBL4526947 | 0.92 | KCNH2 (0.36) | KCNH2CYP3A4TNFLITAF | |
| SCHEMBL4516695 | 0.92 | KCNH2 (0.36) | KCNH2CYP3A4TNFLITAF | |
| SCHEMBL1383304 | 0.90 | — | — | |
| SCHEMBL4501334 | 0.90 | KCNH2 (0.36) | KCNH2TNFLITAF | |
| SCHEMBL4511256 | 0.90 | KCNH2 (0.36) | KCNH2TNFLITAF | |
| SCHEMBL5909017 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-B1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 2008-06-11 | — | — | EP | claimed |
| US-7094780-B1 | 3-aminoquinazolin-2,4-dione antibacterial agents | WARNER LAMBERT COMPANY LLC (US) | 2006-08-22 | — | — | US | claimed |