SCHEMBL476238

SCHEMBL476238

C=CCOC(=O)C(C)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7937962 0.98 TDP1 (0.44)
SCHEMBL4675440 0.84
SCHEMBL7572557 0.83 TDP1 (0.43)
SCHEMBL5875837 0.82 TDP1 (0.44)
SCHEMBL6476278 0.81 TDP1 (0.48)
SCHEMBL536216 0.81
SCHEMBL3747997 0.81 TSHR (0.32)
SCHEMBL3747995 0.81 TSHR (0.32)
SCHEMBL7575794 0.81 TDP1 (0.42)
SCHEMBL7132868 0.81 TDP1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114262414-B Comb-type ultra-high molecular weight polymer and synthesis method thereof 长春市兆兴新材料技术有限责任公司 2024-07-05 CN claimed
CN-113501894-B Methacrylate copolymer based on photocatalysis and medical optical polymer 福州大学 2022-07-26 CN claimed
CN-113717301-B High-activity free radical polymerization system based on oxygen-heterocyclic aromatic photocatalyst 福州大学 2022-05-24 CN claimed
CN-113717301-A High-activity free radical polymerization system based on oxygen-heterocyclic photocatalyst 福州大学 2021-11-30 CN claimed
CN-113501894-A Methacrylate copolymer based on photocatalysis and medical optical polymer 福州大学 2021-10-15 CN claimed
WO-2012146978-A2 A NOVEL PROCESS FOR THE PREPARATION OF TAPENTADOL OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF ACTAVIS GROUP PTC EHF (IS) 2012-11-01 WO claimed
EP-1773856-B1 PREPARATION OF ALKYL-SUBSTITUTED 2-DEOXY-2-FLUORO-D-RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES PHARMASSET INC (US) 2012-02-01 EP claimed
US-7601820-B2 Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives PHARMASSET, INC. (US) 2009-10-13 US claimed
EP-1773856-A2 PREPARATION OF ALKYL-SUBSTITUTED 2-DEOXY-2-FLUORO-D-RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES Pharmasset, Inc. (US) 2007-04-18 EP claimed
US-20060199783-A1 Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives PHARMASSETT, INC. (US) 2006-09-07 US claimed
WO-2006012440-A2 PREPARATION OF ALKYL-SUBSTITUTED 2-DEOXY-2-FLUORO-D-RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES PHARMASSET, INC. (US) 2006-02-02 WO claimed
EP-0973714-A2 PRODUCTION OF RACEMIC 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID OR PRECURSORS THEREOF ALBEMARLE CORPORATION (US) 2000-01-26 EP claimed
US-5792886-A METHYLATION OF 6-BROMO-2-NAPHTHOL WITH METHYL BROMIDE TO 2-BROMO-6-METHOXYNAPHTHALENE; FORMING GRIGNARD; REACTING WITH A LOWER ALKYL 2-BROMOPROPIONATE ALBEMARLE CORPORATION (US) 1998-08-11 US claimed
WO-1998030528-A2 PRODUCTION OF RACEMIC 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID OR PRECURSORS THEREOF ALBEMARLE CORPORATION (US) 1998-07-16 WO claimed
EP-0041921-B1 PROCESS FOR THE PREPARATION OF N-(1'-ALKOXYCARBONYLETHYL)-2,6-DIALKYL ANILINES CIBA-GEIGY AG (CH) 1983-10-26 EP claimed
US-4266071-A Process for the preparation of N-(1-alkoxycarbonylethyl)-2,6-dialkylanilines CIBA-GEIGY CORPORATION (US) 1981-05-05 US claimed
US-3975432-A Process for preparing 2-(6-methoxy-2-naphthyl)propionic acid SYNTEX CORPORATION (PM) 1976-08-17 US claimed
US-20250034638-A1 Articles with Photoiniferter Attached to Inorganic Oxide Surface and Polymers Prepared Therefrom 3M INNOVATIVE PROPERTIES COMPANY 2025-01-30 US disclosed
US-4266071-A Process for the preparation of N-(1-alkoxycarbonylethyl)-2,6-dialkylanilines CIBA-GEIGY CORPORATION (US) 1981-05-05 US disclosed
US-3970678-A Organotin mercaptide process CINCINNATI MILACRON CHEMICALS, INC. (US) 1976-07-20 US disclosed