Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 14/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3017065 | 1.00 | S1PR1 (0.66) | S1PR1KMT2ACYP3A4ADAMTS5MMP2 | |
| SCHEMBL2998253 | 0.80 | S1PR1 (1.00) | S1PR1ADAMTS5MMP2 | |
| SCHEMBL3959994 | 0.80 | S1PR1 (1.00) | S1PR1ADAMTS5MMP2 | |
| SCHEMBL3009963 | 0.79 | S1PR1 (0.78) | S1PR1ADAMTS5MMP2 | |
| SCHEMBL3009959 | 0.79 | S1PR1 (0.78) | S1PR1ADAMTS5MMP2 | |
| SCHEMBL2998776 | 0.78 | S1PR1 (1.00) | S1PR1ADAMTS5MMP2 | |
| SCHEMBL13211155 | 0.76 | S1PR1 (1.00) | S1PR1ADAMTS5MMP2 | |
| SCHEMBL3020767 | 0.76 | S1PR1 (1.00) | S1PR1ADAMTS5MMP2 | |
| SCHEMBL3008715 | 0.76 | S1PR1 (0.73) | S1PR1ADAMTS5MMP2 | |
| SCHEMBL2998672 | 0.75 | S1PR1 (1.00) | S1PR1ADAMTS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979332-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007083089-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-07-26 | — | — | WO | disclosed |