Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 7/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863581 | 0.93 | BRD4 (0.50) | BRD4TLR7PIK3CDPIK3CAMTOR | |
| SCHEMBL4763092 | 0.86 | TLR7 (0.62) | BRD4TLR7PIK3CDPIK3CAMTOR | |
| SCHEMBL4792376 | 0.85 | BRD4 (0.50) | BRD4TLR7PIK3CDPIK3CAMTOR | |
| SCHEMBL4791772 | 0.85 | TLR7 (0.47) | BRD4TLR7PIK3CDPIK3CAMTOR | |
| SCHEMBL1486674 | 0.84 | TLR7 (0.49) | BRD4TLR7PIK3CDPIK3CAMTOR | |
| SCHEMBL14465891 | 0.81 | BRD4 (0.44) | BRD4TLR7PIK3CDPIK3CAMTOR | |
| SCHEMBL4791340 | 0.81 | BRD4 (0.47) | BRD4TLR7PIK3CDPIK3CAMTOR | |
| SCHEMBL4893805 | 0.81 | BRD4 (0.48) | BRD4TLR7PIK3CDPIK3CAMTOR | |
| SCHEMBL4793608 | 0.80 | TLR7 (0.54) | BRD4TLR7PIK3CDPIK3CAMTOR | |
| SCHEMBL14466846 | 0.79 | BRD4 (0.47) | BRD4TLR7PIK3CDPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968587-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS | Coley Pharmaceutical, Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007075468-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007075468-A1 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZONAPHTHYRIDINES, AND IMIDAZOPYRIDINES, COMPOSITIONS, AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-07-05 | — | — | WO | disclosed |