SCHEMBL4763552

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2265776	0.90	LCK (0.69)	LCKBRAFKDRMAPK14TEK
	SCHEMBL4765562	0.88	LCK (1.00)	LCKBRAFKDRMAPK14TEK
	SCHEMBL4772175	0.87	LCK (0.60)	LCKBRAFKDRMAPK14TEK
	SCHEMBL11889149	0.83	LCK (0.75)	LCKBRAFKDRMAPK14TEK
	SCHEMBL22025872	0.83	LCK (0.69)	LCKBRAFKDRMAPK14TEK
	SCHEMBL11889240	0.82	LCK (0.73)	LCKBRAFKDRMAPK14TEK
	SCHEMBL2263560	0.82	LCK (0.73)	LCKBRAFKDRMAPK14TEK
	SCHEMBL22025874	0.82	BRAF (0.81)	LCKBRAFKDRMAPK14TEK
	SCHEMBL2265325	0.82	LCK (0.73)	LCKBRAFKDRMAPK14TEK
	SCHEMBL2264401	0.81	BRAF (0.81)	LCKBRAFKDRMAPK14TEK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.