Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.75 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.75 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.66 |
| ▸ | TTR | P02766 | 1/20 | 0.66 |
| ▸ | SHBG | P04278 | 1/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.66 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.66 |
| ▸ | CBR1 | P16152 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758120 | 1.00 | ESR1 (0.75) | ESR1ESR2CYP19A1CYP3A4AKR1B1 | |
| SCHEMBL27715512 | 0.88 | PLK1 (0.68) | ESR1ESR2CYP19A1CYP3A4MEN1 | |
| SCHEMBL30269741 | 0.86 | ESR1 (1.00) | ESR1ESR2CYP19A1CYP3A4AKR1B1 | |
| SCHEMBL28130871 | 0.86 | ESR1 (1.00) | ESR1ESR2CYP19A1CYP3A4AKR1B1 | |
| SCHEMBL31551707 | 0.86 | ESR1 (1.00) | ESR1ESR2CYP19A1CYP3A4AKR1B1 | |
| SCHEMBL617168 | 0.84 | KMT2A (0.70) | ESR1ESR2CYP19A1CYP3A4AKR1B1 | |
| SCHEMBL31173021 | 0.84 | MAPT (0.70) | ESR1ESR2CYP19A1CYP3A4AKR1B1 | |
| SCHEMBL13893460 | 0.82 | ESR1 (0.82) | ESR1ESR2CYP19A1CYP3A4AKR1B1 | |
| SCHEMBL27950798 | 0.82 | ESR1 (0.70) | ESR1ESR2CYP19A1CYP3A4AKR1B1 | |
| SCHEMBL4758965 | 0.82 | CYP19A1 (0.61) | ESR1ESR2CYP19A1CYP3A4AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102229967-B | Method for preparing cartharein and isocartharein from naringenin | UNIV SHANGHAI OF T C M | 2013-04-10 | — | — | CN | claimed |
| CN-102229967-A | Method for preparing cartharein and isocartharein from naringenin | UNIV SHANGHAI OF T C M | 2011-11-02 | — | — | CN | claimed |
| CN-100421685-C | Chinese material medica preparation in use for treating infection of influenza virus, and preparation method | TIANJIN MEDICINES INST (CN) | 2008-10-01 | — | — | CN | claimed |
| CN-118995656-A | Demethylation functional enzyme of flavonoid compound, and encoding gene and application thereof | 上海中医药大学 | 2024-11-22 | — | — | CN | disclosed |
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |
| CN-109568472-A | A kind of Chinese medicine preparation and preparation method thereof for treating gastritis | 贾建真 | 2019-04-05 | — | — | CN | disclosed |
| CN-108853428-A | A kind of Chinese medicine preparation by improving immunity anticancer | 四川能节环保科技有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108815286-A | It is a kind of to prevent and treat sick Chinese herbal and crude drugs preparations of the rotten son of honeybee and preparation method thereof and method of administration | 博罗县柏塘丰养蜂专业合作社 | 2018-11-16 | — | — | CN | disclosed |
| CN-108208402-A | The Chinese medicine additive of one boar food | 贵州泓耀食品股份有限公司 | 2018-06-29 | — | — | CN | disclosed |
| CN-107929449-A | The method for preventing perch saprolegniasis | 钦州市钦州港高丰水产养殖专业合作社 | 2018-04-20 | — | — | CN | disclosed |
| CN-104983845-B | Treat the Chinese herbal medicine of seawater fish skin ulcer | 河北科技师范学院 | 2018-01-26 | — | — | CN | disclosed |
| CN-1965978-A | Natural botanical extraction liquid for preventing and treating epidemic febrile disease of birds and livestock and method for preparing same | YANGZHONG MULE PHARMACEUTICAL (CN) | 2007-05-23 | — | — | CN | disclosed |
| US-20070110832-A1 | SCUTELLARIA BARBATA EXTRACT FOR THE TREATMENT OF CANCER | BIONOVO, INC. (US) | 2007-05-17 | — | — | US | disclosed |
| CN-1180815-C | Tumor treating medicine | 于玺长 | 2004-12-22 | — | — | CN | disclosed |
| CN-1416850-A | Compound fig prepn for preventing and treating cancer and its prepn process | ZHENPING BIOLOG SCI TECH I XIN (CN) | 2003-05-14 | — | — | CN | disclosed |
| CN-1383856-A | Tumor treating medicine | YU XICHANG (CN) | 2002-12-11 | — | — | CN | disclosed |
| CN-1071098-C | Globeflower tea and its production method | ZHANG JINGLI (CN) | 2001-09-19 | — | — | CN | disclosed |
| CN-1211394-A | Globeflower tea and its production method | ZHANG JINGLI (CN) | 1999-03-24 | — | — | CN | disclosed |
| US-5688628-A | ACID FORMER, POLYMERS, PHENOLIC COMPOUND | NIPPON ZEON CO., LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| EP-0742012-A2 | Pharmaceutical composition containing substance inhibiting HSP47 production | Kureha Chemical Industry Co., Ltd. (JP) | 1996-11-13 | — | — | EP | disclosed |