Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4278301 | 0.90 | KDR (0.74) | KDRFGFR1 | |
| SCHEMBL4286004 | 0.85 | KDR (1.00) | KDRFGFR1 | |
| SCHEMBL4287296 | 0.84 | KDR (1.00) | KDRFGFR1 | |
| SCHEMBL4291658 | 0.84 | KDR (0.71) | KDRFGFR1 | |
| SCHEMBL4432118 | 0.84 | KDR (0.73) | KDRFGFR1 | |
| SCHEMBL4292548 | 0.84 | KDR (0.76) | KDRFGFR1 | |
| SCHEMBL4282097 | 0.83 | KDR (0.78) | KDRFGFR1 | |
| SCHEMBL4279794 | 0.83 | KDR (0.78) | KDRFGFR1 | |
| SCHEMBL4287888 | 0.83 | KDR (0.82) | KDRFGFR1 | |
| SCHEMBL4283277 | 0.83 | KDR (0.83) | KDRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904498-A1 | FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007004749-A1 | FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-11 | — | — | WO | disclosed |