Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12371183 | 0.81 | TSHR (0.48) | TSHRLMNAALDH1A1ALOX15ACP3 | |
| SCHEMBL28856440 | 0.75 | TSHR (0.57) | TSHRLMNAALDH1A1ALOX15ACP3 | |
| SCHEMBL4093002 | 0.74 | TSHR (0.67) | TSHRLMNAALDH1A1ALOX15ACP3 | |
| SCHEMBL8002226 | 0.72 | TSHR (0.53) | TSHRLMNAALDH1A1ALOX15ACP3 | |
| SCHEMBL27326877 | 0.72 | TSHR (0.53) | TSHRLMNAALDH1A1ALOX15ACP3 | |
| SCHEMBL11707796 | 0.71 | TSHR (0.57) | TSHRLMNAALDH1A1ALOX15ACP3 | |
| SCHEMBL11332099 | 0.71 | ACP3 (0.55) | TSHRLMNAALDH1A1ALOX15ACP3 | |
| SCHEMBL11432821 | 0.71 | TSHR (0.61) | TSHRLMNAALDH1A1ALOX15ACP3 | |
| SCHEMBL384083 | 0.71 | TSHR (0.61) | TSHRLMNAALDH1A1ALOX15ACP3 | |
| SCHEMBL254876 | 0.71 | TSHR (0.61) | TSHRLMNAALDH1A1ALOX15ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879895-A1 | ENZYME INHIBITORS | Chroma Therapeutics Limited (GB) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117549-A1 | ENZYME INHIBITORS | CHROMA THERAPEUTICS LTD (GB) | 2006-11-09 | — | — | WO | disclosed |