Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19223052 | 0.83 | KDR (0.69) | KDR | |
| SCHEMBL4278057 | 0.83 | KDR (0.60) | KDR | |
| SCHEMBL25403926 | 0.77 | RAF1 (0.45) | KDR | |
| SCHEMBL4287177 | 0.76 | KDR (0.60) | KDR | |
| SCHEMBL4287330 | 0.76 | KDR (0.72) | KDR | |
| SCHEMBL4286007 | 0.75 | KDR (0.51) | KDR | |
| SCHEMBL4287337 | 0.74 | KDR (1.00) | KDR | |
| SCHEMBL4284980 | 0.74 | KDR (0.56) | KDR | |
| SCHEMBL4291635 | 0.73 | KDR (1.00) | KDR | |
| SCHEMBL4287531 | 0.73 | KDR (0.83) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904498-A1 | FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007004749-A1 | FUSED HETEROCYCLIC DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-11 | — | — | WO | disclosed |