SCHEMBL4765016

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11888972	0.93	LCK (0.56)	LCKBRAFKDRMAPK14TEK
	SCHEMBL11889409	0.93	LCK (0.56)	LCKBRAFKDRMAPK14TEK
	SCHEMBL4772175	0.88	LCK (0.60)	LCKBRAFKDRMAPK14TEK
	SCHEMBL4768484	0.87	BRAF (0.59)	LCKBRAFKDRMAPK14TEK
	SCHEMBL4763359	0.86	LCK (0.56)	LCKBRAFKDRMAPK14TEK
	SCHEMBL2264429	0.86	LCK (0.56)	LCKBRAFKDRMAPK14TEK
	SCHEMBL5471596	0.86	LCK (0.54)	LCKBRAFKDRMAPK14TEK
	SCHEMBL4764961	0.86	BRAF (0.56)	LCKBRAFKDRMAPK14TEK
	SCHEMBL11967615	0.86	LCK (0.53)	LCKBRAFKDRMAPK14TEK
	SCHEMBL11889161	0.85	BRAF (0.52)	LCKBRAFKDRMAPK14TEK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.