Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Butane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL23567204 | 1.00 | — | — | |
| Butane SCHEMBL27543855 | 0.93 | — | — | |
| Butane SCHEMBL9978624 | 0.93 | — | — | |
| Butane SCHEMBL2979230 | 0.93 | — | — | |
| Butane SCHEMBL9442188 | 0.93 | — | — | |
| Butane SCHEMBL8463912 | 0.93 | — | — | |
| Butane SCHEMBL5129860 | 0.93 | TSHR (0.44) | — | |
| Butane SCHEMBL454368 | 0.93 | — | — | |
| Butane SCHEMBL8412888 | 0.93 | TSHR (0.44) | — | |
| Butane SCHEMBL11809277 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107216446-B | A kind of polymerization of catalyst/initiator system for being catalyzed initiation caprolactone polymerization and the caprolactone using it | 北京服装学院 | 2019-09-13 | — | — | CN | claimed |
| CN-109897072-A | A kind of polymerization of carbon monoxide-olefin polymeric and the caprolactone using the carbon monoxide-olefin polymeric containing iron complex and its preparation and comprising it | 北京服装学院 | 2019-06-18 | — | — | CN | claimed |
| CN-107216446-A | It is a kind of to be used to be catalyzed the catalyst/initiator system for triggering caprolactone polymerization and the polymerization using its caprolactone | 北京服装学院 | 2017-09-29 | — | — | CN | claimed |
| CN-109897072-B | Iron-containing complex, preparation thereof, catalyst composition containing iron-containing complex and polymerization of caprolactone by using catalyst composition | 北京服装学院 | 2021-05-18 | — | — | CN | disclosed |
| CN-109694465-B | Thiophene copolymer and preparation method and application thereof | 深圳清华大学研究院 | 2021-03-30 | — | — | CN | disclosed |
| CN-107216446-B | A kind of polymerization of catalyst/initiator system for being catalyzed initiation caprolactone polymerization and the caprolactone using it | 北京服装学院 | 2019-09-13 | — | — | CN | disclosed |
| CN-109897072-A | A kind of polymerization of carbon monoxide-olefin polymeric and the caprolactone using the carbon monoxide-olefin polymeric containing iron complex and its preparation and comprising it | 北京服装学院 | 2019-06-18 | — | — | CN | disclosed |
| CN-109134229-A | A method of preparing cypress oleyl alcohol | 中国农业科学院农业环境与可持续发展研究所 | 2019-01-04 | — | — | CN | disclosed |
| CN-107216446-A | It is a kind of to be used to be catalyzed the catalyst/initiator system for triggering caprolactone polymerization and the polymerization using its caprolactone | 北京服装学院 | 2017-09-29 | — | — | CN | disclosed |
| EP-0989993-B1 | TARTRATE SALT OF A SUBSTITUTED DIPEPTIDE AS GROWTH HORMONE SECRETAGOGUE | PFIZER PROD INC (US) | 2008-03-05 | — | — | EP | disclosed |
| CN-1524857-A | Tartrate salt of a substituted dipeptide as growth hormone secretagogue | �Ʒ� | 2004-09-01 | — | — | CN | disclosed |
| US-6596867-B2 | Bone disorders | PFIZER INC. | 2003-07-22 | — | — | US | disclosed |
| CN-1314912-A | Tartrate salt of substituted dipeptide as growth hormone secretagogue | PFIZER PROD INC (US) | 2001-09-26 | — | — | CN | disclosed |
| US-20010016570-A1 | Tartrate salt of a substituded dipeptide as growth hormone secretagogue | RAQUALIA PHARMA INC. (JP) | 2001-08-23 | — | — | US | disclosed |
| US-6248717-B1 | TREATMENT OF OSTEOPOROSIS, CARDIOTONIC AGENTS, ANTIAGING AGENTS, WOUND HEALING AGENTS | PFIZER INC. | 2001-06-19 | — | — | US | disclosed |
| EP-0989993-A1 | TARTRATE SALT OF A SUBSTITUTED DIPEPTIDE AS GROWTH HORMONE SECRETAGOGUE | Pfizer Products Inc. (US) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998058948-A1 | TARTRATE SALT OF A SUBSTITUTED DIPEPTIDE AS GROWTH HORMONE SECRETAGOGUE | PFIZER PRODUCTS INC. (US) | 1998-12-30 | — | — | WO | disclosed |
| CN-1030704-C | Process for polymerizing monomers comprising at least one conjugated diene | ENICHEM ELASTOMERS (IT) | 1996-01-17 | — | — | CN | disclosed |
| CN-87103699-A | Molecular Weight Regulators for Lanthanide and Actinide Catalysts | — | 1988-09-21 | — | — | CN | disclosed |