Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660192 | 1.00 | ESR1 (0.41) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL4661315 | 0.91 | ESR1 (0.44) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL5435957 | 0.90 | MEN1 (0.41) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL5433411 | 0.90 | MEN1 (0.41) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL6411925 | 0.89 | ESR1 (0.42) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL4661319 | 0.89 | ESR1 (0.42) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL4659971 | 0.89 | ESR1 (0.42) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL4661524 | 0.89 | ESR1 (0.42) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL4659994 | 0.89 | ESR1 (0.40) | ESR1ESR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL4660067 | 0.81 | ESR1 (0.52) | ESR1ESR2MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620102-B1 | 3-(1-NAPHTHYL)-2-CYANOPROPANOIC ACID DERIVATIVES AS ESTROGEN RECEPTOR LIGANDS | WYETH CORP (US) | 2008-12-24 | — | — | EP | disclosed |