⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14041118 | 0.74 | — | — | |
| SCHEMBL14342886 | 0.70 | MEN1 (0.36) | — | |
| SCHEMBL28258268 | 0.70 | MEN1 (0.36) | — | |
| SCHEMBL28205887 | 0.70 | MEN1 (0.36) | — | |
| SCHEMBL27583411 | 0.69 | — | — | |
| SCHEMBL9526013 | 0.63 | — | — | |
| SCHEMBL20365190 | 0.61 | — | — | |
| SCHEMBL14041078 | 0.57 | — | — | |
| SCHEMBL3910040 | 0.55 | TRIM24 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1771294 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412078-B1 | PROCESSES FOR THE PRODUCTION OF AMINO-PROTECTED DERIVATIVES OF 4-AMINOMETHYLENE-PYRROLIDIN-3-ONE, GEMIFLOXACIN OR A SALT THEREOF | LG LIFE SCIENCES LTD (KR) | 2008-10-08 | — | — | EP | disclosed |
| US-7199242-B2 | Processes for the production of amino-protected derivatives of 4-aminomethylene-pyrrolidin-3-one and/or 4-aminomethylene-pyrrolidin-3-alkoxyimino derivatives and/or gemifloxacin or a salt thereof | LG LIFE SCIENCES LIMITED (KR) | 2007-04-03 | — | — | US | disclosed |
| US-7199242-B2 | Processes for the production of amino-protected derivatives of 4-aminomethylene-pyrrolidin-3-one and/or 4-aminomethylene-pyrrolidin-3-alkoxyimino derivatives and/or gemifloxacin or a salt thereof | LG LIFE SCIENCES LIMITED (KR) | 2007-04-03 | — | — | US | disclosed |
| US-20050043546-A1 | Processes for the production of amino-protected derivatives of 4-aminomethylene-pyrrolidin-3-one and/or 4-aminomethylene-pyrrolidin-3-alkoxyimino derivatives and/or gemifloxacin or a salt thereof | LG CHEM, LTD. (KR) | 2005-02-24 | — | — | US | disclosed |
| US-20050043546-A1 | Processes for the production of amino-protected derivatives of 4-aminomethylene-pyrrolidin-3-one and/or 4-aminomethylene-pyrrolidin-3-alkoxyimino derivatives and/or gemifloxacin or a salt thereof | LG CHEM, LTD. (KR) | 2005-02-24 | — | — | US | disclosed |
| EP-1412078-A1 | PROCESSES FOR THE PRODUCTION OF AMINO-PROTECTED DERIVATIVES OF 4-AMINOMETHYLENE-PYRROLIDIN-3-ONE AND/OR 4-AMINOMETHYLENE-PYRROLIDIN-3-ALKOXYIMINO DERIVATIVES AND/OR GEMIFLOXACIN OR A SALT THEREOF | SB Pharmco Puerto Rico Inc (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003011450-A1 | PROCESSES FOR THE PRODUCTION OF AMINO-PROTECTED DERIVATIVES OF 4-AMINOMETHYLENE-PYRROLIDIN-3-ONE AND/OR 4-AMINOMETHYLENE-PYRROLIDIN-3-ALKOXYIMINO DERIVATIVES AND/OR GEMIFLOXACIN OR A SALT THEREOF | LG LIFE SCIENCES LIMITED (KR) | 2003-02-13 | — | — | WO | disclosed |