SCHEMBL4765730

SCHEMBL4765730

Cc1nc2c(cc1C(F)(F)F)N(Cc1ccc(OC(=O)O)s1)CCCC2N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1nnn(C)n1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4775434 0.92 CETP (0.51) CETP
SCHEMBL2479335 0.89 CETP (0.53) CETP
SCHEMBL4774468 0.85 CETP (0.52) CETP
SCHEMBL4768511 0.85 CETP (0.50) CETP
SCHEMBL2475665 0.84 CETP (0.50) CETP
SCHEMBL4768408 0.84 CETP (0.51) CETP
SCHEMBL4773127 0.83 CETP (0.48) CETP
SCHEMBL4767444 0.82 CETP (0.52) CETP
SCHEMBL4768789 0.82 CETP (0.51) CETP
SCHEMBL4773128 0.81 CETP (0.52) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1732933-B1 COMPOUNDS FOR TREATING DYSLIPIDEMIA LILLY CO ELI (US) 2008-07-23 EP claimed