SCHEMBL4766029

SCHEMBL4766029

CC(C)N1C(=O)CC2(CCCN(C3CCN(C(=O)c4cc(-c5ccccn5)sc4NC(=O)O)CC3)C2)C1=O

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACACB O00763 19/20 0.54
ACACA Q13085 18/20 0.54
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3498420 0.94 ACACB (0.53) ACACBACACACYP2C9
SCHEMBL4766278 0.92 ACACB (0.48) ACACBACACACYP2C9
SCHEMBL13312717 0.91 ACACB (0.49) ACACBACACACYP2C9
SCHEMBL4724543 0.90 ACACB (0.45) ACACBACACACYP2C9
SCHEMBL4722214 0.90 ACACB (0.44) ACACBACACACYP2C9
SCHEMBL3495837 0.89 ACACB (0.50) ACACBACACACYP2C9
SCHEMBL4721010 0.86 ACACB (0.53) ACACBACACACYP2C9
SCHEMBL3496515 0.85 ACACB (0.46) ACACBACACACYP2C9
SCHEMBL3498406 0.84 ACACB (0.57) ACACBACACACYP2C9
SCHEMBL3497215 0.84 ACACB (0.52) ACACBACACACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1911753-A1 SPIRO-CYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2008-04-16 EP disclosed