Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 19/20 | 0.60 |
| ▸ | CDK2 | P24941 | 19/20 | 0.60 |
| ▸ | CCND1 | P24385 | 15/20 | 0.60 |
| ▸ | CDK6 | Q00534 | 15/20 | 0.60 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.60 |
| ▸ | CDK9 | P50750 | 5/20 | 0.60 |
| ▸ | CDK4 | P11802 | 4/20 | 0.60 |
| ▸ | CCND3 | P30281 | 1/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3675736 | 1.00 | CCNE1 (0.60) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL3673181 | 0.95 | CCNE1 (0.56) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL918045 | 0.95 | CCNE1 (0.67) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL3674787 | 0.93 | CCNE1 (0.53) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL3679347 | 0.91 | CCNE1 (0.53) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL3672972 | 0.91 | CCNE1 (0.62) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL3668200 | 0.91 | CCNE1 (0.62) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL3669727 | 0.91 | CCNE1 (0.62) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL917525 | 0.90 | CCNE1 (0.59) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL3669459 | 0.89 | CCNE1 (0.67) | CCNE1CDK2CCND1CDK6CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931667-A1 | PYRIDO-PYRIDIMIDINE DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007036791-A1 | PYRIDO-PYRIDIMIDINE DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2007-04-05 | — | — | WO | disclosed |