Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476697 | 0.87 | CNR1 (0.39) | CNR1CNR2 | |
| SCHEMBL476416 | 0.86 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL476342 | 0.85 | CNR1 (0.41) | CNR1CNR2 | |
| SCHEMBL476430 | 0.82 | CNR1 (0.40) | CNR1CNR2 | |
| SCHEMBL2682366 | 0.80 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL7902981 | 0.78 | CNR1 (0.40) | CNR1CNR2 | |
| SCHEMBL2681558 | 0.76 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL2682922 | 0.76 | CNR1 (0.33) | CNR1CNR2 | |
| SCHEMBL2681835 | 0.76 | CNR1 (0.39) | CNR1CNR2 | |
| SCHEMBL2682017 | 0.76 | CNR1 (0.42) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411383-B1 | DERIVATIVES OF 3-ALKOXY-4,5-DIARYLTHIOPHENE-2-CARBOXAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-10-22 | — | — | EP | claimed |
| EP-2411383-A1 | DERIVATIVES OF 3-ALKOXY-4,5-DIARYLTHIOPHENE-2-CARBOXAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-02-01 | — | — | EP | claimed |
| WO-2010109150-A1 | DERIVATIVES OF 3-ALKOXY-4,5-DIARYLTHIOPHENE-2-CARBOXAMIDE, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-09-30 | — | — | WO | claimed |