Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 7/20 | 0.53 |
| ▸ | LCLAT1 | Q6UWP7 | 2/20 | 0.50 |
| ▸ | RAF1 | P04049 | 6/20 | 0.46 |
| ▸ | BRAF | P15056 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4764238 | 0.89 | IL2 (0.66) | IL2RAF1BRAFMAPK14 | |
| SCHEMBL4792182 | 0.86 | IL2 (0.44) | IL2LCLAT1RAF1BRAFMAPK14 | |
| SCHEMBL4769520 | 0.83 | STIM1 (0.52) | IL2RAF1BRAFMAPTMAPK14 | |
| SCHEMBL4761831 | 0.82 | IL2 (0.55) | IL2RAF1BRAFMAPK14 | |
| SCHEMBL1825914 | 0.81 | IL2 (0.51) | IL2MAPTIDO1 | |
| SCHEMBL4768106 | 0.80 | MAPK14 (0.45) | IL2RAF1BRAFMAPK14 | |
| SCHEMBL1827582 | 0.79 | MEN1 (0.50) | IL2LCLAT1MAPTIDO1 | |
| SCHEMBL2814805 | 0.78 | IL2 (0.53) | IL2RAF1BRAF | |
| SCHEMBL8297609 | 0.77 | IL2 (0.58) | IL2 | |
| SCHEMBL8296797 | 0.77 | MEN1 (0.55) | MAPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846372-A4 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2008-12-17 | — | — | EP | disclosed |
| EP-1846372-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | Synta Pharmaceuticals Corporation (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006083477-A2 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2006-08-10 | — | — | WO | disclosed |