Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 3/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482796 | 0.90 | KDR (0.53) | TDP1KDRKMT2AMEN1MET | |
| SCHEMBL4490967 | 0.82 | NPC1 (0.54) | KDRKMT2AMEN1METRAB9A | |
| SCHEMBL4491792 | 0.82 | MEN1 (0.57) | KDRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL4481741 | 0.80 | KDR (0.48) | KDRMETRAB9ANPC1KIT | |
| SCHEMBL4473087 | 0.79 | FLT3 (0.58) | KDRMETKITPDGFRAPDGFRB | |
| SCHEMBL4472148 | 0.79 | IDO1 (0.46) | KDRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL4465203 | 0.79 | KDR (0.47) | KDRKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL4480257 | 0.77 | KDR (0.50) | KDRKMT2AMEN1METRAB9A | |
| SCHEMBL4472965 | 0.77 | KMT2A (0.55) | KDRKMT2AMEN1RAB9AKIT | |
| SCHEMBL4473208 | 0.76 | EPHX2 (0.50) | KDRKMT2AMEN1RAB9AKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851198-B1 | SUBSTITUTED PYRROLES, COMPOSITIONS CONTAINING SAME, METHOD FOR MAKING SAME AND USE THEREOF | AVENTIS PHARMA SA (FR) | 2008-12-31 | — | — | EP | claimed |