Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147102 | 0.80 | HDAC1 (0.48) | HDAC1HDAC6KDM4ETSHRALDH1A1 | |
| SCHEMBL5147159 | 0.79 | HDAC1 (0.45) | HDAC1HDAC6KDM4ETSHRALDH1A1 | |
| SCHEMBL4768253 | 0.78 | HDAC1 (0.44) | HDAC1HDAC6KDM4ETSHRALDH1A1 | |
| SCHEMBL5147071 | 0.78 | HDAC1 (0.39) | HDAC1HDAC6KDM4ECA1CA2 | |
| SCHEMBL4768273 | 0.76 | HDAC1 (0.42) | HDAC1HDAC6TP53CREBBPHDAC10 | |
| SCHEMBL5147104 | 0.75 | HDAC1 (0.48) | HDAC1HDAC6KDM4ETSHRALDH1A1 | |
| SCHEMBL4771960 | 0.69 | CYP3A4 (0.43) | HDAC1HDAC6KDM4EALDH1A1TP53 | |
| SCHEMBL4772324 | 0.69 | HDAC1 (0.39) | HDAC1HDAC6ALDH1A1TP53CREBBP | |
| SCHEMBL5145477 | 0.69 | HDAC1 (0.46) | HDAC1HDAC6KDM4ETSHRALDH1A1 | |
| SCHEMBL5147126 | 0.69 | HDAC1 (0.46) | HDAC1HDAC6KDM4ETP53CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924557-A2 | CARBAZOLE DERIVATIVES | Serenex, Inc. (US) | 2008-05-28 | — | — | EP | claimed |
| US-20070185184-A1 | Carbazole derivatives | SERENEX, INC. | 2007-08-09 | — | — | US | claimed |
| WO-2007035620-A2 | CARBAZOLE DERIVATIVES | SERENEX, INC. (US) | 2007-03-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185184-A1 | Carbazole derivatives | CCNI, MKI67, CCNB3 | HDAC1 145/4885HDAC6 204/4885KDM4E 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.