Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 18/20 | 0.68 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926722 | 0.91 | PTGER1 (0.61) | PTGER1KDM1AMAPT | |
| SCHEMBL4774737 | 0.83 | PTGER1 (0.80) | PTGER1MAPT | |
| SCHEMBL4771655 | 0.83 | PTGER1 (0.80) | PTGER1MAPT | |
| SCHEMBL4765663 | 0.82 | PTGER1 (0.65) | PTGER1KDM1AMAPT | |
| SCHEMBL4770373 | 0.82 | PTGER1 (0.78) | PTGER1KDM1A | |
| SCHEMBL4720675 | 0.82 | MAPT (0.58) | PTGER1KDM1AMAPT | |
| SCHEMBL4772723 | 0.81 | PTGER1 (0.61) | PTGER1KDM1AMAPT | |
| SCHEMBL4917838 | 0.81 | PTGER1 (1.00) | PTGER1 | |
| SCHEMBL14008141 | 0.81 | PTGER1 (0.70) | PTGER1KDM1A | |
| SCHEMBL4924137 | 0.80 | PTGER1 (0.75) | PTGER1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2008-11-20 | — | — | US | disclosed |
| EP-1874749-A1 | FURAN COMPOUNDS USEFUL AS EPl RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006114272-A1 | FURAN COMPOUNDS USEFUL AS EPl RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287430-A1 | Furan Compounds Useful As Ep1 Receptor Antagonists | PTGER1, PTGER2, PTGER3 | PTGER1 1/4885KDM1A 1744/4885MAPT 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.