SCHEMBL4768800

SCHEMBL4768800

NC(=O)N1C=CC=CS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30026724 0.67
SCHEMBL27566586 0.61
SCHEMBL5672376 0.60
SCHEMBL21617580 0.59
SCHEMBL3181122 0.59
SCHEMBL28823438 0.57
SCHEMBL9549412 0.55
Urea SCHEMBL4468827 0.49
SCHEMBL5944764 0.48
Urea SCHEMBL11630931 0.46

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107922400-B Muscarinic M1 receptor positive allosteric modulators 苏文生命科学有限公司 2021-05-11 CN claimed
EP-1322627-A1 CYCLIC SULFONYL COMPOUNDS AS INHIBITORS OF METALLOPROTEASES Bristol-Myers Squibb Pharma Company (US) 2003-07-02 EP claimed
WO-2002028846-A1 CYCLIC SULFONYL COMPOUNDS AS INHIBITORS OF METALLOPROTEASES DUPONT PHARMACEUTICALS COMPANY (US) 2002-04-11 WO claimed
CN-108276359-B Benzothiazinone compound, preparation method and pharmaceutical application thereof 复旦大学 2021-09-07 CN disclosed
CN-107922400-B Muscarinic M1 receptor positive allosteric modulators 苏文生命科学有限公司 2021-05-11 CN disclosed
EP-1971596-A2 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS Takeda Pharmaceutical Company Limited (JP) 2008-09-24 EP disclosed
WO-2007077961-A2 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS MINERALOCORTICOID RECEPTOR LIGANDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-07-12 WO disclosed
EP-1322627-A1 CYCLIC SULFONYL COMPOUNDS AS INHIBITORS OF METALLOPROTEASES Bristol-Myers Squibb Pharma Company (US) 2003-07-02 EP disclosed
WO-2002028846-A1 CYCLIC SULFONYL COMPOUNDS AS INHIBITORS OF METALLOPROTEASES DUPONT PHARMACEUTICALS COMPANY (US) 2002-04-11 WO disclosed