Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3956518 | 0.83 | CYP2C9 (0.33) | GLA | |
| SCHEMBL4765372 | 0.80 | GLA (0.37) | GLA | |
| SCHEMBL6211933 | 0.80 | GLA (0.37) | GLA | |
| SCHEMBL4769145 | 0.72 | CAPN1 (0.39) | — | |
| SCHEMBL4769153 | 0.72 | CAPN1 (0.39) | — | |
| SCHEMBL6590820 | 0.69 | EPHX1 (0.40) | GLA | |
| SCHEMBL20069277 | 0.69 | SMN1; SMN2 (0.36) | TRPV1CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL28677420 | 0.68 | SMN1; SMN2 (0.35) | TRPV1CNR1CNR2 | |
| SCHEMBL15055259 | 0.64 | KDM4E (0.38) | — | |
| SCHEMBL7421894 | 0.63 | CPN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320370-A4 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORP (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1320370-A1 | METHOD OF TREATMENT | SmithKline Beecham Corporation (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002017924-A1 | METHOD OF TREATMENT | SMITHKLINE BEECHAM CORPORATION (GB) | 2002-03-07 | — | — | WO | disclosed |