Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.70 |
| ▸ | CA9 | Q16790 | 8/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.70 |
| ▸ | GLA | P06280 | 4/20 | 0.70 |
| ▸ | GAA | P10253 | 4/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 5/20 | 0.63 |
| ▸ | CA6 | P23280 | 4/20 | 0.63 |
| ▸ | CA7 | P43166 | 4/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.63 |
| ▸ | CA4 | P22748 | 3/20 | 0.63 |
| ▸ | CA5A | P35218 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | GBA1 | P04062 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27265450 | 0.90 | CA9 (0.71) | CA12CA9KDM4EGLAGAA | |
| SCHEMBL3989449 | 0.88 | KMT2A (0.67) | CA12CA9KDM4EGLAGAA | |
| SCHEMBL17090847 | 0.86 | CA12 (0.68) | CA12CA9KDM4EGLAGAA | |
| SCHEMBL3469861 | 0.86 | CA12 (0.66) | CA12CA9KDM4EGLAGAA | |
| SCHEMBL29961174 | 0.85 | CA12 (0.66) | CA12CA9KDM4EGLAGAA | |
| SCHEMBL21043916 | 0.85 | CA12 (0.64) | CA12CA9KDM4EGLAGAA | |
| SCHEMBL3438690 | 0.85 | CA12 (0.62) | CA12CA9KDM4EGLAGAA | |
| SCHEMBL19900141 | 0.84 | KDM4E (0.65) | CA12CA9KDM4EGLAGAA | |
| SCHEMBL25543534 | 0.84 | CA12 (0.69) | CA12CA9KDM4EGLAGAA | |
| SCHEMBL1095981 | 0.84 | CA12 (0.63) | CA12CA9KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11519014-B2 | Specific substrate of an ALDH isoenzyme | ADVANCED BIODESIGN (FR) | 2022-12-06 | — | — | US | disclosed |
| US-20190233871-A1 | SPECIFIC SUBSTRATE OF AN ALDH ISOENZYME | ADVANCED BIODESIGN (FR) | 2019-08-01 | — | — | US | disclosed |
| EP-3491143-A1 | SPECIFIC SUBSTRATE OF AN ALDH ISOENZYME | Advanced Biodesign (FR) | 2019-06-05 | — | — | EP | disclosed |
| EP-2001463-A1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | Council of Scientific and Industrial Research (IN) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007107846-A1 | A PHARMACEUTICAL COMPOSITION USEFUL AS ACETYL CHOLINESTERASE INHIBITORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-09-27 | — | — | WO | disclosed |