Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180252 | 0.94 | BTK (0.43) | BTKSSTR1SSTR4GAAKDM1A | |
| SCHEMBL2490017 | 0.94 | BTK (0.43) | BTKSSTR1SSTR4GAAKDM1A | |
| SCHEMBL13767380 | 0.94 | BTK (0.43) | BTKSSTR1SSTR4GAAKDM1A | |
| SCHEMBL2490021 | 0.94 | BTK (0.43) | BTKSSTR1SSTR4GAAKDM1A | |
| SCHEMBL2180249 | 0.94 | BTK (0.43) | BTKSSTR1SSTR4GAAKDM1A | |
| SCHEMBL30111928 | 0.94 | BTK (0.43) | BTKSSTR1SSTR4GAAKDM1A | |
| SCHEMBL2180246 | 0.94 | BTK (0.43) | BTKSSTR1SSTR4GAAKDM1A | |
| SCHEMBL14040699 | 0.87 | BTK (0.42) | BTKGAAKDM1AMAOBEPHX1 | |
| SCHEMBL4765504 | 0.87 | BTK (0.42) | BTKGAAKDM1AMAOBEPHX1 | |
| SCHEMBL14131624 | 0.87 | BTK (0.42) | BTKGAAKDM1AMAOBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992628-A1 | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones | GLAXO GROUP LIMITED (GB) | 2008-11-19 | — | — | EP | disclosed |