SCHEMBL4771006

SCHEMBL4771006

COCCn1c(-c2ccc(C(C)C)cc2)nc2cccc(OC)c21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CASR P41180 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2500508 0.85 CASR (0.76) CASR
SCHEMBL2498541 0.83 CASR (0.73) CASR
SCHEMBL13136642 0.83 CASR (0.73) CASR
SCHEMBL14397254 0.83 CASR (0.73) CASR
SCHEMBL2497994 0.82 CASR (0.70) CASR
SCHEMBL2495098 0.82 CASR (0.71) CASR
SCHEMBL2498850 0.82 CASR (0.69) CASR
SCHEMBL2497105 0.81 CASR (0.70) CASR
SCHEMBL2498300 0.81 CASR (1.00) CASR
SCHEMBL2500093 0.81 CASR (0.68) CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2004629-A2 BENZIMIDAZOLE DERIVATIVES Novartis AG (CH) 2008-12-24 EP disclosed
WO-2007112913-A2 BENZIMIDAZOLE DERIVATIVES NOVARTIS AG (CH) 2007-10-11 WO disclosed