Phenylalanine

Phenylalanine

SCHEMBL4771386

N[C@@H](Cc1ccccc1)C(=O)O.N[C@H](CCC(=O)O)C(=O)O

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.76
ALPI P09923 1/20 0.76
PKM P14618 1/20 0.76
PTGS1 P23219 1/20 0.76
XIAP P98170 1/20 0.76
SLC15A1 P46059 1/20 0.65
SLC1A3 P43003 3/20 0.62
SLC1A2 P43004 3/20 0.62
SLC1A1 P43005 3/20 0.62
GRIA2 P42262 2/20 0.62
CYP1A2 P05177 2/20 0.62
GRM8 O00222 1/20 0.62
GRM6 O15303 1/20 0.62
GRIN2D O15399 1/20 0.62
GRIN3B O60391 1/20 0.62
GSR P00390 1/20 0.62
GRIK1 P39086 1/20 0.62
GRM5 P41594 1/20 0.62
GRIA1 P42261 1/20 0.62
GRIA3 P42263 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL4869932 1.00 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL22500896 1.00 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8541118 1.00 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL3742888 1.00 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL1458889 1.00 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL23152420 0.95 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL21410077 0.95 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL20994022 0.95 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL3735371 0.95 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL1921833 0.94 SLC7A5 (0.67) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1998791-A1 SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN Salpep Biotechnology, Inc. (CA) 2008-12-10 EP disclosed
WO-2007112556-A1 SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN SALPEP BIOTECHNOLOGY INC. (CA) 2007-10-11 WO disclosed