Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 3/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768768 | 0.90 | PTGDR (0.53) | PTGDRALDH1A1CYP3A4CYP2C9PTGS2 | |
| SCHEMBL2242475 | 0.86 | PTGDR (0.54) | PTGDRTDP1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2238098 | 0.86 | PTGDR (0.53) | PTGDRTDP1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2237693 | 0.83 | PTGDR (0.73) | PTGDRKMT2A | |
| SCHEMBL2240945 | 0.81 | GBA1 (0.54) | PTGDRALDH1A1CYP3A4CYP2C9MAPT | |
| SCHEMBL2239971 | 0.81 | SMN1; SMN2 (0.53) | PTGDRMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2237295 | 0.80 | CYP2A6 (0.45) | PTGDRKDM4EALDH1A1KCNH2CYP3A4 | |
| SCHEMBL2237320 | 0.80 | HIF1A (0.47) | PTGDRKDM4EALDH1A1KCNH2CYP3A4 | |
| SCHEMBL2238820 | 0.80 | PTGDR (0.48) | PTGDRKDM4EALDH1A1KCNH2CYP3A4 | |
| SCHEMBL2241291 | 0.80 | KMT2A (0.46) | PTGDRTDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1878733-A1 | Pyrimidine derivatives as ALK-5 inhibitors | Novartis AG (CH) | 2008-01-16 | — | — | EP | disclosed |