Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 10/20 | 0.57 |
| ▸ | RIPK3 | Q9Y572 | 8/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477030 | 0.88 | CSNK1E (0.70) | CSNK1ERIPK3 | |
| SCHEMBL476993 | 0.81 | RIPK3 (0.60) | CSNK1ERIPK3HASPINCSNK1D | |
| SCHEMBL477085 | 0.78 | CSNK1E (0.76) | CSNK1ERIPK3HASPIN | |
| SCHEMBL476996 | 0.76 | CSNK1E (0.74) | CSNK1ERIPK3 | |
| SCHEMBL477170 | 0.76 | CSNK1E (0.74) | CSNK1ERIPK3 | |
| SCHEMBL476995 | 0.76 | CSNK1E (0.74) | CSNK1ERIPK3 | |
| SCHEMBL3119264 | 0.75 | CSNK1E (0.77) | CSNK1ERIPK3CSNK1D | |
| SCHEMBL477045 | 0.74 | CSNK1E (1.00) | CSNK1ERIPK3HASPIN | |
| SCHEMBL477035 | 0.69 | CSNK1E (0.71) | CSNK1ERIPK3HASPIN | |
| SCHEMBL477163 | 0.69 | CSNK1E (0.64) | CSNK1ERIPK3HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331546-B1 | 2-ALKYL-6-CYCLOAMINO-3-(PYRIDIN-4-YL)IMIDAZO[1,2-IB]-PYRIDAZINE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2012-02-01 | — | — | EP | claimed |