⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26719873 | 0.85 | — | — | |
| SCHEMBL26719874 | 0.85 | — | — | |
| SCHEMBL26719876 | 0.85 | — | — | |
| SCHEMBL1615049 | 0.69 | TSHR (0.39) | — | |
| SCHEMBL2757919 | 0.67 | — | — | |
| SCHEMBL1025861 | 0.66 | TSHR (0.36) | — | |
| SCHEMBL1021983 | 0.66 | TSHR (0.36) | — | |
| Fluoride SCHEMBL11522295 | 0.66 | TSHR (0.36) | — | |
| SCHEMBL1021515 | 0.66 | TSHR (0.36) | — | |
| SCHEMBL3116631 | 0.66 | TSHR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170051145-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE (US) | 2017-02-23 | — | — | US | disclosed |
| US-9522980-B2 | Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20110275734-A1 | NON-REACTIVE, HYDROPHILIC POLYMERS HAVING TERMINAL SILOXANES AND METHODS FOR MAKING AND USING THE SAME | JOHNSON & JOHNSON VISION CARE, INC. | 2011-11-10 | — | — | US | disclosed |