Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 14/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16591356 | 0.95 | TSHR (0.59) | TSHRGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL1022208 | 0.95 | TSHR (0.67) | TSHRGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL19975633 | 0.94 | TSHR (0.66) | TSHRGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL14012885 | 0.93 | TSHR (0.57) | TSHRGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL18643015 | 0.93 | TSHR (0.64) | TSHRGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL20066976 | 0.93 | TSHR (0.64) | TSHRGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL983174 | 0.92 | TSHR (0.66) | TSHRGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL980008 | 0.91 | TSHR (0.64) | TSHRGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL1840088 | 0.91 | TSHR (0.64) | TSHRGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL1954247 | 0.91 | TSHR (0.64) | TSHRGAAMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11829008-B2 | Increased stiffness center optic in soft contact lenses for astigmatism correction | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11820850-B2 | Polymer compositions containing grafted polymeric networks and processes for their preparation and use | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-11754754-B2 | Silicone hydrogels comprising N-alkyl methacrylamides and contact lenses made thereof | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2023-09-12 | — | — | US | disclosed |
| US-10036899-B2 | Multi-piece insert device with glue seal for ophthalmic devices | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20180210231-A1 | Ophthalmic Apparatus with a Passive Event-Based Coloration System | JOHNSON & JOHNSON VISION CARE (US) | 2018-07-26 | — | — | US | disclosed |
| US-20180203253-A1 | METHODS AND APPARATUS TO ENHANCE OXYGEN CONCENTRATIONS FOR OPHTHALMIC DEVICES | JOHNSON & JOHNSON VISION CARE (US) | 2018-07-19 | — | — | US | disclosed |
| US-20180203257-A1 | METHODS AND APPARATUS TO ENHANCE OXYGEN CONCENTRATIONS FOR ADVANCED OPHTHALMIC DEVICES | JOHNSON & JOHNSON VISION CARE (US) | 2018-07-19 | — | — | US | disclosed |
| US-20180203254-A1 | METHODS AND APPARATUS TO ENHANCE OXYGEN CONCENTRATIONS FOR ADVANCED OPHTHALMIC DEVICES | JOHNSON & JOHNSON VISION CARE (US) | 2018-07-19 | — | — | US | disclosed |
| US-20180203256-A1 | METHODS AND APPARATUS TO ENHANCE OXYGEN CONCENTRATIONS FOR ADVANCED OPHTHALMIC DEVICES | JOHNSON & JOHNSON VISION CARE (US) | 2018-07-19 | — | — | US | disclosed |
| US-20180203255-A1 | METHODS AND APPARATUS TO ENHANCE OXYGEN CONCENTRATIONS FOR ADVANCED OPHTHALMIC DEVICES | JOHNSON & JOHNSON VISION CARE (US) | 2018-07-19 | — | — | US | disclosed |
| US-20090146329-A1 | LENS RELEASE | JOHNSON & JOHNSON VISION CARE, INC. | 2009-06-11 | — | — | US | disclosed |
| US-7473738-B2 | Lactam polymer derivatives | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2009-01-06 | — | — | US | disclosed |
| US-20080273168-A1 | ANTIMICROBIAL LENSES, PROCESSES TO PREPARE THEM AND METHODS OF THEIR USE | JOHNSON & JOHNSON VISION CARE, INC. | 2008-11-06 | — | — | US | disclosed |
| US-20080103231-A1 | PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JOHNSON & JOHNSON VISION CARE, INC. | 2008-05-01 | — | — | US | disclosed |
| US-20080045612-A1 | Wettable hydrogels comprising acyclic polyamides | JOHNSON & JOHNSON VISION CARE, INC | 2008-02-21 | — | — | US | disclosed |
| US-20070290174-A1 | LACTAM POLYMER DERIVATIVES | JOHNSON & JOHNSON VISION CARE, INC. | 2007-12-20 | — | — | US | disclosed |
| US-20070222095-A1 | PROCESS FOR MAKING OPHTHALMIC LENSES | JOHNSON & JOHNSON VISION CARE, INC. | 2007-09-27 | — | — | US | disclosed |
| US-20070222094-A1 | Process for making ophthalmic lenses | JOHNSON & JOHNSON VISION CARE, INC. | 2007-09-27 | — | — | US | disclosed |
| US-20070138692-A1 | PROCESS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES | JOHNSON & JOHNSON VISION CARE, INC. | 2007-06-21 | — | — | US | disclosed |
| US-20070043140-A1 | Method for the mitigation of symptoms of contact lens related dry eye | JOHNSON & JOHNSON VISION CARE, INC. | 2007-02-22 | — | — | US | disclosed |