Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23795927 | 1.00 | TDP1 (0.60) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL590360 | 0.90 | TDP1 (0.54) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL590359 | 0.90 | TDP1 (0.54) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL27716950 | 0.85 | TDP1 (0.62) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL15505335 | 0.83 | TDP1 (0.65) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL5680637 | 0.82 | TDP1 (0.62) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL13306408 | 0.82 | TDP1 (0.56) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL5199651 | 0.82 | MEN1 (0.55) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL13504656 | 0.82 | TDP1 (0.54) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL8892710 | 0.82 | MEN1 (0.55) | TDP1MEN1GAAKMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996579-A2 | ANTIBIOTIC COMPOUNDS | Actelion Pharmaceuticals Ltd. (CH) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007105154-A2 | ANTIBIOTIC COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2007-09-20 | — | — | WO | disclosed |
| EP-1799676-A2 | NEW BICYCLIC ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006032466-A2 | NEW BICYCLIC ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2006-03-30 | — | — | WO | disclosed |