Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130666 | 0.91 | BRD9 (0.40) | BRD9BRD7IDH1PDE7AHRH3 | |
| SCHEMBL4144552 | 0.90 | BRD9 (0.40) | BRD9BRD7IDH1PDE7AHRH3 | |
| SCHEMBL4136350 | 0.88 | BRD9 (0.39) | BRD9BRD7IDH1PDE7AHRH3 | |
| SCHEMBL4131005 | 0.86 | IDH1 (0.37) | BRD9BRD7IDH1PDE7AHRH3 | |
| SCHEMBL4139655 | 0.84 | IDH1 (0.46) | BRD9BRD7IDH1GRIA2HTR2A | |
| SCHEMBL4128876 | 0.82 | HRH3 (0.43) | HRH3OTUD7BPIK3CACYP1A2CYP3A4 | |
| SCHEMBL4145752 | 0.79 | IDH1 (0.36) | BRD9BRD7IDH1HRH3GRIA2 | |
| SCHEMBL4152594 | 0.78 | IDH1 (0.36) | BRD9BRD7IDH1GRIA2HTR2A | |
| SCHEMBL4136323 | 0.75 | IDH1 (0.39) | BRD9BRD7IDH1GRIA2HTR2C | |
| SCHEMBL4140498 | 0.72 | HRH3 (0.49) | HRH3OTUD7BCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007749-A2 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | Pfizer Products Inc. (US) | 2008-12-31 | — | — | EP | claimed |
| WO-2007105053-A2 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-09-20 | — | — | WO | claimed |