SCHEMBL4773570

SCHEMBL4773570

CNC(=O)[C@H](N)CCCN

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 8/20 0.51
DPP8 Q6V1X1 5/20 0.51
DPP9 Q86TI2 5/20 0.51
DPP4 P27487 3/20 0.51
GNAI3 P08754 1/20 0.50
GNAO1 P09471 1/20 0.50
GNAI1 P63096 1/20 0.50
GSR P00390 1/20 0.48
RRM1 P23921 1/20 0.44
SLC15A1 P46059 1/20 0.44
MMP2 P08253 1/20 0.40
LTA4H P09960 1/20 0.38
TERT O14746 1/20 0.38
TLR2 O60603 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14456838 1.00 DPP7 (0.51) DPP7DPP8DPP9DPP4GNAI3
SCHEMBL8528049 1.00 DPP7 (0.51) DPP7DPP8DPP9DPP4GNAI3
Hydrochloric Acid SCHEMBL8015391 0.98 DPP7 (0.50) DPP7DPP8DPP9DPP4GNAI3
Hydrochloric Acid SCHEMBL8015394 0.98 DPP7 (0.50) DPP7DPP8DPP9DPP4GNAI3
Hydrochloric Acid SCHEMBL8526234 0.98 DPP7 (0.50) DPP7DPP8DPP9DPP4GNAI3
SCHEMBL6014706 0.94 GSR (0.57) DPP7DPP8DPP9DPP4GNAI3
SCHEMBL19080648 0.94 GSR (0.57) DPP7DPP8DPP9DPP4GNAI3
SCHEMBL463468 0.94 GSR (0.57) DPP7DPP8DPP9DPP4GNAI3
SCHEMBL8403553 0.89 DPP7 (0.48) DPP7DPP8DPP9DPP4GNAI3
SCHEMBL20366099 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1940785-A2 ACYCLIC 1,4-DIAMINES AND USES THEREOF SmithKline Beecham Corporation (US) 2008-07-09 EP claimed
WO-2007030761-A2 ACYCLIC 1,4-DIAMINES AND USES THEREOF SMITHKLINE BEECHAM CORPORATION (US) 2007-03-15 WO claimed
EP-2897622-B1 METHODS FOR TREATMENT OR PREVENTION OF DAMAGE RESULTING FROM RADIATION SYNEDGEN INC (US) 2021-04-21 EP disclosed
WO-2014197763-A1 MOLECULAR DESIGN TOWARD DUAL-MODALITY PROBES FOR RADIOISOTOPE-BASED IMAGING (PET OR SPECT) AND MRI THE BOARD OF REGENTS OF THE UNIVERSITY OF TEAS SYSTEM (US) 2014-12-11 WO disclosed
EP-1940785-A2 ACYCLIC 1,4-DIAMINES AND USES THEREOF SmithKline Beecham Corporation (US) 2008-07-09 EP disclosed
WO-2007030761-A2 ACYCLIC 1,4-DIAMINES AND USES THEREOF SMITHKLINE BEECHAM CORPORATION (US) 2007-03-15 WO disclosed
US-5545624-A USEFUL IN TREATING BACTERIAL OR MYCOPLASMIC INFECTIONS PFIZER INC. (US) 1996-08-13 US disclosed