Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.37 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4140140 | 0.92 | CAPN1 (0.43) | CAPN1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL4136304 | 0.82 | CAPN1 (0.53) | CAPN1BMP1CCR1ADAM17CTSL | |
| SCHEMBL5434636 | 0.80 | CAPN1 (0.51) | CAPN1BMP1CCR1ADAM17CTSL | |
| SCHEMBL4777748 | 0.80 | CAPN1 (0.40) | CAPN1BMP1CCR1ADAM17CTSL | |
| SCHEMBL4139968 | 0.79 | CAPN1 (0.44) | CAPN1BMP1CCR1ADAM17CTSL | |
| SCHEMBL4140823 | 0.79 | CAPN1 (0.46) | CAPN1BMP1CCR1ADAM17CTSL | |
| SCHEMBL4141710 | 0.78 | CAPN1 (0.49) | CAPN1BMP1CCR1ADAM17CTSL | |
| SCHEMBL4141985 | 0.78 | CAPN1 (0.46) | CAPN1BMP1CCR1ADAM17CTSL | |
| SCHEMBL4142973 | 0.78 | CAPN1 (0.48) | CAPN1BMP1CCR1ADAM17CTSL | |
| SCHEMBL4130820 | 0.77 | CAPN1 (0.47) | CAPN1BMP1CCR1ADAM17CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940785-A2 | ACYCLIC 1,4-DIAMINES AND USES THEREOF | SmithKline Beecham Corporation (US) | 2008-07-09 | — | — | EP | claimed |
| WO-2007030761-A2 | ACYCLIC 1,4-DIAMINES AND USES THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-15 | — | — | WO | claimed |