Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4523602 | 0.83 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL4523607 | 0.83 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL4511255 | 0.78 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL4511249 | 0.78 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL4793018 | 0.77 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL4793690 | 0.77 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL4517407 | 0.77 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL4522169 | 0.76 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL4497260 | 0.76 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL4498765 | 0.76 | KCNH2 (0.61) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891078-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006125974-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |