Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ABL2 | P42684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774221 | 1.00 | KMT2A (0.46) | KMT2AHTTMEN1ALDH1A1GRIN2B | |
| SCHEMBL4021076 | 0.93 | GRIN2B (0.45) | KMT2AHTTMEN1ALDH1A1GRIN2B | |
| SCHEMBL4021079 | 0.93 | GRIN2B (0.45) | KMT2AHTTMEN1ALDH1A1GRIN2B | |
| SCHEMBL4024200 | 0.89 | KMT2A (0.41) | KMT2AHTTMEN1ALDH1A1GRIN2B | |
| SCHEMBL4024195 | 0.89 | KMT2A (0.41) | KMT2AHTTMEN1ALDH1A1GRIN2B | |
| SCHEMBL4021403 | 0.87 | KMT2A (0.45) | KMT2AHTTMEN1ALDH1A1KDM2B | |
| SCHEMBL4021402 | 0.87 | KMT2A (0.45) | KMT2AHTTMEN1ALDH1A1KDM2B | |
| SCHEMBL4021772 | 0.83 | KMT2A (0.53) | KMT2AMEN1ALDH1A1GRIN2BKDM2B | |
| SCHEMBL4021770 | 0.83 | KMT2A (0.53) | KMT2AMEN1ALDH1A1GRIN2BKDM2B | |
| SCHEMBL4751419 | 0.81 | MEN1 (0.40) | KMT2AMEN1ALDH1A1GRIN2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |