Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.61 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.57 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776856 | 0.86 | CRBN (0.52) | CRBNDDB1IKZF3 | |
| SCHEMBL4780875 | 0.84 | CRBN (0.68) | CRBNDDB1IKZF3 | |
| SCHEMBL4794565 | 0.83 | CRBN (0.52) | CRBNDDB1IKZF3 | |
| SCHEMBL4776021 | 0.81 | CRBN (0.61) | CRBNDDB1IKZF3 | |
| SCHEMBL4776830 | 0.81 | CRBN (0.57) | CRBNDDB1IKZF3 | |
| SCHEMBL4780718 | 0.78 | CRBN (0.61) | CRBNDDB1IKZF3 | |
| SCHEMBL20811949 | 0.78 | CRBN (0.83) | CRBNDDB1IKZF3 | |
| SCHEMBL19359394 | 0.75 | CRBN (0.64) | CRBNDDB1IKZF3 | |
| SCHEMBL17336169 | 0.75 | CRBN (0.64) | CRBNDDB1IKZF3 | |
| SCHEMBL25290471 | 0.74 | CRBN (0.81) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008007979-A1 | (2,6-DIOXO-3-PIPERINYL)AMIDOBENZOIC IMMUNOMODULATORY AND ANTI-CANCER DERIVATIVES | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-01-17 | — | — | WO | claimed |
| WO-2008007979-A1 | (2,6-DIOXO-3-PIPERINYL)AMIDOBENZOIC IMMUNOMODULATORY AND ANTI-CANCER DERIVATIVES | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008007979-A1 | (2,6-DIOXO-3-PIPERINYL)AMIDOBENZOIC IMMUNOMODULATORY AND ANTI-CANCER DERIVATIVES | AUCKLAND UNISERVICES LIMITED (NZ) | 2008-01-17 | — | — | WO | disclosed |