Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 11/20 | 0.82 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.57 |
| ▸ | EDNRB | P24530 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4773774 | 0.90 | EDNRA (1.00) | EDNRAAGTR1AGTR2 | |
| SCHEMBL6938266 | 0.88 | EDNRA (0.80) | EDNRAAGTR1AGTR2EDNRB | |
| SCHEMBL4766782 | 0.83 | EDNRA (0.74) | EDNRAAGTR1AGTR2 | |
| SCHEMBL5530761 | 0.82 | EDNRA (0.80) | EDNRAAGTR1AGTR2 | |
| SCHEMBL5534079 | 0.82 | EDNRA (0.80) | EDNRAAGTR1AGTR2 | |
| SCHEMBL4769864 | 0.82 | EDNRA (0.79) | EDNRAAGTR1AGTR2 | |
| SCHEMBL4774226 | 0.82 | EDNRA (0.84) | EDNRAAGTR1AGTR2 | |
| SCHEMBL4773927 | 0.81 | EDNRA (0.83) | EDNRAAGTR1AGTR2 | |
| SCHEMBL5536056 | 0.81 | EDNRA (0.78) | EDNRAAGTR1AGTR2 | |
| SCHEMBL4770295 | 0.81 | EDNRA (0.83) | EDNRAAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094816-B1 | BIPHENYL SULFONAMIDES AS DUAL ANGIOTENSIN ENDOTHELIN RECEPTOR ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2008-12-10 | — | — | EP | disclosed |