Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775297 | 1.00 | MEN1 (0.34) | MEN1KMT2AEPHX1ATMSERPINE1 | |
| SCHEMBL28444127 | 0.87 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL9561774 | 0.85 | EPHX1 (0.46) | EPHX1NAAA | |
| SCHEMBL9561777 | 0.85 | EPHX1 (0.46) | EPHX1NAAA | |
| SCHEMBL9561874 | 0.83 | EPHX1 (0.49) | EPHX1NAAA | |
| SCHEMBL9862944 | 0.83 | EPHX1 (0.49) | EPHX1NAAA | |
| SCHEMBL9561873 | 0.83 | EPHX1 (0.49) | EPHX1NAAA | |
| SCHEMBL4781593 | 0.78 | ATM (0.37) | MEN1KMT2AATMSERPINE1 | |
| SCHEMBL4781594 | 0.78 | ATM (0.37) | MEN1KMT2AATMSERPINE1 | |
| SCHEMBL4625976 | 0.76 | ATM (0.36) | MEN1KMT2AEPHX1ATMSERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008004788-A1 | NOVEL DERIVATIVES OF CYCLIC COMPOUND AND THE USE THEREOF | WONKISOPHARM CO., LTD. (KR) | 2008-01-10 | — | — | WO | claimed |
| US-8420853-B2 | Derivatives of cyclic compound and the use thereof | Wonkisopharm Co., Ltd (KR) | 2013-04-16 | — | — | US | disclosed |
| WO-2008004788-A1 | NOVEL DERIVATIVES OF CYCLIC COMPOUND AND THE USE THEREOF | WONKISOPHARM CO., LTD. (KR) | 2008-01-10 | — | — | WO | disclosed |