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Sugi Predict / Compounds / SCHEMBL4775701

SCHEMBL4775701

SCHEMBL4775701

CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCCN(OC(=O)OC(C)(C)C)c2cc(C(F)(F)F)c(C)nc21

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CETP P11597 18/20 0.43
▸ TACR1 P25103 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4768208 0.90 CETP (0.51) CETP
SCHEMBL4775685 0.88 CETP (0.45) CETPTACR1
SCHEMBL4774914 0.81 CETP (0.56) CETP
SCHEMBL4772767 0.79 CETP (0.43) CETP
SCHEMBL4768336 0.78 CETP (0.64) CETP
SCHEMBL4765965 0.76 CETP (0.66) CETP
SCHEMBL4770764 0.76 CETP (0.56) CETP
SCHEMBL4765951 0.76 CETP (0.49) CETP
SCHEMBL4772751 0.76 CETP (0.64) CETP
SCHEMBL14410748 0.76 CETP (0.37) CETPTACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1732933-B1 COMPOUNDS FOR TREATING DYSLIPIDEMIA LILLY CO ELI (US) 2008-07-23 — — EP claimed