Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775785 | 1.00 | CYP2E1 (0.40) | CYP2E1CSF1RFYNAPOBEC3AAPOBEC3G | |
| SCHEMBL4140094 | 0.95 | CYP2E1 (0.36) | CYP2E1APOBEC3AAPOBEC3GSYK | |
| SCHEMBL4140087 | 0.95 | CYP2E1 (0.36) | CYP2E1APOBEC3AAPOBEC3GSYK | |
| SCHEMBL14291278 | 0.93 | CSF1R (0.35) | CYP2E1CSF1RFYNF2MAPK14 | |
| SCHEMBL4838993 | 0.89 | CYP2E1 (0.36) | CYP2E1APOBEC3AAPOBEC3GSYK | |
| SCHEMBL4838987 | 0.89 | CYP2E1 (0.36) | CYP2E1APOBEC3AAPOBEC3GSYK | |
| Ammonia Solution, Strong SCHEMBL4156140 | 0.88 | CYP2E1 (0.36) | CYP2E1APOBEC3AAPOBEC3GSYK | |
| Ammonia Solution, Strong SCHEMBL4156138 | 0.88 | CYP2E1 (0.36) | CYP2E1APOBEC3AAPOBEC3GSYK | |
| SCHEMBL4152953 | 0.87 | KDM4E (0.37) | SYK | |
| SCHEMBL4152956 | 0.87 | KDM4E (0.37) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | claimed |