Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 8/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019768 | 0.94 | KMT2A (0.36) | KMT2AHTTALDH1A1LMNAKDM2B | |
| SCHEMBL4022184 | 0.92 | KMT2A (0.36) | KMT2AHTTALDH1A1LMNAKDM2B | |
| SCHEMBL4029278 | 0.91 | KMT2A (0.36) | KMT2AHTTALDH1A1LMNAKDM2B | |
| SCHEMBL4026486 | 0.90 | KMT2A (0.35) | KMT2AHTTALDH1A1LMNAKDM2B | |
| SCHEMBL4028175 | 0.87 | KDM2B (0.41) | KMT2AHTTALDH1A1LMNAKDM2B | |
| SCHEMBL4023590 | 0.83 | DRD4 (0.39) | KMT2AHTTALDH1A1LMNAMCHR1 | |
| SCHEMBL4023604 | 0.80 | KDM2B (0.42) | KMT2AHTTALDH1A1LMNAKDM2B | |
| SCHEMBL13721307 | 0.78 | KDM2B (0.43) | KMT2AHTTALDH1A1LMNAKDM2B | |
| SCHEMBL4018780 | 0.78 | KDM2B (0.43) | KMT2AHTTALDH1A1LMNAKDM2B | |
| SCHEMBL4018783 | 0.78 | KDM2B (0.43) | KMT2AHTTALDH1A1LMNAKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |